Successful alopecia universalis treatment with the combination of cyclosporine and oral corticosteroid: a case report

Background: Alopecia universalis is an autoimmune condition on hair follicles with the characteristics of ovoid or round-shaped loss (focal) that develops into multiple losses and most severe form alopecia. The pathogenesis alopecia unclear. However, accepted hypothesis based immunologic factor, especially T-cell mediated process. Case: A 19-year-old male Indonesian complained all over his body. Efflorescence whole body showed patch. Severity Tool (SALT) score 100%. Skin dermoscopy indicated yellow dots. patient was given 8 mg intraoral methylprednisolone every hours 100 cyclosporine 12 for four weeks slowly tapering off. experienced acneiform eruption topically treated 2% sulfur lotion hours. After 51 days observation, improvement found in terminal growth head, eyelashes, eyebrows, visible vellus body, a SALT 40%. Conclusion: rare can cause significant damage psychological pressure to affected individuals. Treatment corticosteroid resulted good therapy response.